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Mean Contact Data

The following table shows the number of contacts made at each position and the mean percentage burial of the residue at that location.

RES CDR ALL SMALL MEDIUM LARGE
H97 H3 22 46.3 7 18.4 8 51.7 7 75.8
L91 L3 21 74.5 8 76.0 8 82.9 5 61.1
L96 L3 21 59.4 10 62.4 5 53.1 6 62.1
L94 L3 21 23.0 7 13.4 8 25.1 6 33.0
H52 H2 19 53.3 4 20.2 8 69.6 7 74.1
H95 H3 18 75.7 7 71.8 5 87.6 6 69.9
H33 H1 18 68.9 6 48.6 5 80.8 7 82.9
H50 H2 18 66.4 5 49.8 7 74.3 6 76.4
L32 L1 18 54.9 5 30.9 7 75.4 6 65.9
H96 H3 15 34.8 6 29.2 4 35.9 5 40.7
H56 H2 15 24.3 3 9.4 6 25.3 6 41.9
L92 L3 14 35.4 2 8.5 4 37.8 8 66.5
L93 L3 14 18.4 4 6.1 3 15.8 7 36.5
L30A L1 12 32.2 4 18.9 7 40.4 1 72.2
H98 H3 12 26.5 3 13.9 5 30.7 4 36.5
H31 H1 12 20.3 1 1.2 3 5.7 8 58.8
H53 H2 11 16.6 1 2.6 6 20.2 4 30.4
H54 H2 11 12.6     4 8.0 7 33.1
H100 H3 10 52.2 4 38.5 4 67.5 2 55.3
H58 H2 10 20.2 2 9.3 5 35.0 3 19.1
H35 H1 9 78.5 6 85.4 1 100.0 2 60.9
L50 L2 9 17.4 1 6.7 2 4.7 6 43.4
H32 H1 8 13.8 1 6.1 1 3.7 6 32.2
L30C L1 7 16.4 2 3.7 4 22.3 1 59.1
H99 H3 6 18.9 1 16.3 3 20.3 2 21.3
L49 L2 6 10.3 2 4.0 1 8.2 3 20.3
L34 L1 5 57.5 3 77.2 1 47.9 1 27.5
H100B H3 5 36.6 3 42.6     2 55.2
H100A H3 5 32.1 2 17.7 2 36.4 1 50.0
H52A H2 5 26.1 1 3.6 3 57.2 1 22.0
H30 H1 5 4.1         5 12.8
H47 H2 4 16.4 2 18.8 1 14.6 1 14.5
L30E L1 4 10.8     3 20.0 1 18.9
L31 L1 4 7.0     1 7.6 3 15.0
L30B L1 4 6.4 1 1.4 2 4.0 1 59.7
L30 L1 4 5.4     1 1.8 3 16.4
H55 H2 4 3.0     2 3.2 2 6.6
L53 L2 3 6.8         3 22.0
H100E H3 2 75.1 1 71.2     1 79.0
H100C H3 2 60.8 1 97.6     1 84.8
L89 L3 2 38.8 2 64.7        
L46 L2 2 5.3 1 9.3 1 7.0    
L30D L1 2 4.8 1 1.6 1 8.2    
L55 L2 2 3.6     1 4.4 1 8.0
H100F H3 1 91.8         1 91.8
H100H H3 1 64.2         1 64.2
H100D H3 1 57.6         1 57.6
L36 L1 1 50.0 1 100.0        
H93 H3 1 33.3 1 50.0        
H31B H1 1 11.1     1 11.1    
H51 H2 1 5.3     1 24.7    
H101 H3 1 1.7     1 4.2    
L52 L2 1 1.1         1 3.6
H57 H2 1 1.0         1 2.9
L56 L2 1 0.9         1 3.1
L54 L2 1 0.2         1 0.7
L67 LFR3 1 0.2         1 0.8
H64 HFR3 1 0.1         1 0.5
L27 L1 1 0.1         1 0.5

All antibody/antigen complexes, total 26.
1baf 1dbb 1eap 1fig 1ibg 1igj 1ind 2cgr 2mcp 4fab 1acy 1cbv 1fpt 1ggi 1him 1mfb 1tet 2igf 1ikf 1jel 1jhl 1mlc 1ncd 1vfb 2hfl 3hfm

Small antigens, total 10
1baf 1dbb 1eap 1fig 1ibg 1igj 1ind 2cgr 2mcp 4fab

Medium antigens, total 8
1acy 1cbv 1fpt 1ggi 1him 1mfb 1tet 2igf

Large antigens, total 8
1ikf 1jel 1jhl 1mlc 1ncd 1vfb 2hfl 3hfm

Notes:

  1. Residue numbering is according to Chothia and Lesk (1987) JMB 196, 901-917 and according to Al-Lazikani et al (1997) rather than other Chothia papers. See here for the reasons why.
  2. CDR definitions are the 'Contact' definitions.
  3. Data are the number of contacts made at each position and the mean percentage burial.
  4. Data are sorted by number of contacts in all antibody/antigen complexes.