www.bioinf.org.uk : Dr. Andrew C.R. Martin's Group
This page allows you to calculate the geminality of a given amino acid sequence relative to the germ-line variables genes from the NCBI databases.
A link to your temporary results file will be returned. The
process of calcuating the germinality index will take approximately
one minute. After this time, a link to the plain text results will
Currently the format of the results can be presented as either comma-separated values (CSV) or as an HTML table.
If you get any error or warning messages, please check you have
entered your sequence correctly. Strange sequence features may cause
the similarity search stage to fail.
Also, long input sequences are truncated at 500 amino acids. . If, after checking your sequence, you still get errors or warnings, please send me an e-mail: and I'll see if the programs can be modified to accomodate your sequence. Alternatively, your antibody may just be very strange!
If you would prefer direct script access, then submit queries to this address using POST or GET 'seqinput'.
Enter the amino acid sequence of your variable region: