Practical 2 Quiz 1

Peptides

1. The torsion angles which describe the protein backbone are:
Alpha, beta, gamma
Phi, psi, omega
Phi, psi, omega, chi

2. The phi angle is defined by the atoms
C-N-CA-C
CA-C-N-CA
N-CA-C-N

3. The psi angle is defined by the atoms
C-N-CA-C
CA-C-N-CA
N-CA-C-N

4. The omega angle is defined by the atoms
C-N-CA-C
CA-C-N-CA
N-CA-C-N

5. The peptide bond is:
A single bond
A double bond
A partial double bond

6. The nature of the peptide bond results from:
Delocalization of a lone pair of electrons on the carbonyl oxygen resulting in a partial positive charge on the oxygen and a partial negative charge on the backbone nitrogen
Delocalization of a lone pair of electrons on the backbone nitrogen resulting in a partial positive charge on the nitrogen and a partial negative charge on the carbonyl oxygen

7. The peptide bond is always:
Close to +/- 90 degrees
Close to 90 degrees
Close to 180 degrees
Close to 0 degrees
Freely rotatable
None of the above

8. Which direction corresponds to a positive torsion angle?
Moving the near atom anti-clockwise or the distant atom clockwise
Moving the near atom clockwise or the distant atom anti-clockwise

9. The peptide bond is often close to 0 degrees when the following amino acid is:
Glycine
Proline
Alanine
Tryptophan

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