Dear Author, We are delighted to inform you that Springer has improved its offprint policy for books! We are now able to satisfy the wish of many authors to receive a pdf of their final contribution in place of the conventional offprint. The final pdf of your chapter in Antibody Engineering book is available in the below path: ftp://Spiproofs:$p!pr0of$@ftp1.spipublisherservices.com/Kontermann_Vol.2/Kontermann_Vol.2_Ch.3_Finalproofs.pdf You may use this document for research and teaching purposes and post it on your homepage. Please always use this version of your contribution in both print and electronic form as it contains the copyright information as well as the correct citation line. If you have not yet registered for the Springer alert service you may wish to consider doing so at www.springer.com. You will find further information on books published in this series at www.springer.com. With best wishes and in the hope that you can make use of this new service! Cordially, Bala on behalf of Springer-Verlag SPi Technologies India Pvt Ltd, Kamak Towers 5th/6th floor, No. 12A, (S.P.), Thiru Vi Ka Industrial Estate, Ekkatuthangal, Guindy, Chennai 600 032, India. Email: e.balamurugan@spi-bpo.com Tel: +91-044-43950500 E-fax: 212 6589035 (USA)